1. (noun) a hereditary disorder of lipid metabolism occurring most frequently in individuals of Jewish descent in eastern Europe; accumulation of lipids in nervous tissue results in death in early childhood

• infantile amaurotic idiocy
• tay-sachs
• tay-sachs disease

1. (noun) a hereditary disorder of lipid metabolism occurring most frequently in individuals of Jewish descent in eastern Europe; accumulation of lipids in nervous tissue results in death in early childhood

• autosomal recessive defect
• autosomal recessive disease
• lipidosis
• monogenic disease
• monogenic disorder