1. (noun) serious weakening and loss of energy

• debilitation
• enervation
• enfeeblement

1. (noun) extreme fatigue

• brain-fag
• mental exhaustion
• frazzle
• inanition

1. (noun) extreme fatigue

• fatigue
• tiredness
• weariness

2. (noun) serious weakening and loss of energy

• weakening

3. (noun) the act of exhausting something entirely

• depletion

1. (noun) serious weakening and loss of energy

• debilitate
• debilitate
• drain
• drain
• enfeeble
• enfeeble
• enervate

2. (noun) the act of exhausting something entirely

• beat
• exhaust
• tucker
• tucker out
• wash up
• consume
• deplete
• eat
• eat up
• exhaust
• run through
• use up
• wipe out
• exhaust
• exhaust
• play out
• run down
• sap
• tire