1. conflict, difference, difference of opinion, dispute

a disagreement or argument about something important

Example Sentences:
'he had a dispute with his wife'
'there were irreconcilable differences'
'the familiar conflict between Republicans and Democrats'

• conflict
• difference
• difference of opinion

2. contravention, dispute

coming into conflict with

• contravention

3. challenge, dispute, gainsay

take exception to

Example Sentences:
'She challenged his claims'

• challenge
• gainsay

4. altercate, argufy, dispute, quarrel, scrap

have a disagreement over something

Example Sentences:
'We quarreled over the question as to who discovered America'
'These two fellows are always scrapping over something'

• altercate
• argufy
• quarrel
• scrap